Achievements

Students of AIP are always encouraged to participate in various festivals, competitions and conferences to develop healthy and competitive spirit. Students have brought many laurels to the institute during last academic sessions.

  • Shivam Yadav (Final year B.Pharm student) received first prize in National Poster Presentation Competition on “Developmental Challenges of Carbon Nano Tubes as a Vaccine Delivery” under the guidance of Dr. Parmesh Kumar Dwivedi.
  • Michael (Final year B.Pharm student) received runners-up trophy at the State round of National Elocution Competition organized by Indian Pharmaceutical Association on 11th October 2017.
  • Abhishek Nayak (B Pharm 2014-18 Batch) had an early joining as Field Sales Officer at Maxzimaa Pharmaceuticals Private Limited, Gorakhpur. Within three months  of joining, he was adjudged as star performer and received best sales award as a fresher.

Abhishek Nayak (B Pharm 2014-18 Batch)

  • Ms. Agrima Srivastava and Mr. Shivam Yadav, students of M. Pharm (Pharmacology) (Second Semester), bagged second prize for making a poster titled ‘Novel Theraputic Target for Neuro-degenerative Disorder’ under the guidance of Dr. Himani Awasthi in ‘SPIRIT 2018’, Annual All India Student's Conclave and a National Seminar organized by the Pharmaceutical Society of IIT (BHU) Varanasi during 3-4 February in 2018 .

Abstract

Novel Theraputic Target for Neuro-degenerative Disorder by Agrima Srivastava, Shivam Yadav and Dr Himani Awasthi (Guide)

Identification of therapeutic targets based on novel mechanism approach is urgently needed for neuro- degenerative disorders such as Alzheimer’s disease, Parkinson’s disease and many more. Limited knowledge of molecular basis of disease, pathogenesis is a major hurdle in the identification of drug targets and development of therapeutic strategies for the largely prevalent disorders. Inhibition of the stress-induced endoplasmic reticulum kinase (Protienkinase RNA like endoplasmic reticulum kinase) may be a potential therapeutic strategy for treating neurodegenerative disorder.

These diseases are usually classified as neuro-degenerative disease that represents a heterogeneous group of disorders characterized by progressive structural or functional neuronal loss or both. Treatment of these disorders is a great challenge due to prevalence of such diseases and the severity of clinical symptoms.

Agrima Srivastava

Shivam Yadav

  • Ms. Nidhi Mishra and Sonam Patel, students of M. Pharm (Pharmacology) second semester, bagged third position for making a poster titled ‘Recent Advances in Treatment of Alzheimer’s Disease’ under the guidance of Dr. Himani Awasthi in ‘SPIRIT 2018’, Annual All India Student's Conclave and a National Seminar organized by the Pharmaceutical Society of IIT (BHU) Varanasi during 3-4 February in 2018.

Abstract

Recent Advances in Treatment of Alzheimer’s Disease by Sonam Patel, Nidhi Mishra and Dr Himani Awasthi (Guide)

Alzheimer’s disease is a neurodegenerative disorder that impairs mainly the memory and cognitive functions in elder people. Various studies conducted recently indicate that Alzheimer’s symptom-reliving drugs have the ability of regulating amyloid precursor protein processing and tau phosphorylation.

It has been proposed that ß-amyloid peptide has a key role in this disease. Several different pharmacological strategies have been developed with the aim of inhibiting the formation of ß-amyloid peptides, such as the inhibitors of ß-secretase and ?-secretase. In addition, anti-amyloid treatments have been developed, which include passive and active immunotherapies focused on inhibiting the aggregation of ß-amyloid peptide.

Advances in the identification of the molecular basis of AD can serve as a model to understand the causes of this neurodegenerative disease. However, the most recent clinical trials in 2 phase III trials with solanezumab, a humanized monoclonal antibody that promotes the clearance of ß-amyloid in the brain, indicate that this antibody does not show efficacy in patients with mild AD, suggesting that rethink this amyloidogenic hypothesis of AD.

Nidhi Mishra

Sonam Patel

Institution/Students Initiatives

Plantation drive

Adoption of village

Celebration of World Pharmacist Day

Wall magazine

Accomplishment of Doctoral / Post Doctoral fellows:

  • Richa Srivastava (Ph.D. scholar) received Best Oral Presentation Award at 7th APS International PharmSCI 2016 on Sinositis at UK under the guidance of Dr. Sajal Srivastava.
  • Richa Srivastava (Ph.D scholar) received Best Oral Presentation Award on “mucoadhesive nasal gel for poly herbal delivery in acute and chronic rhinosinusitis” at ICPHS 2016 under the guidance of Dr. Sajal Srivastava.

Richa Srivastava