Faculty

Dr. Ujjaini Dasgupta
Assistant Professor
Molecular Biology, Biochemistry, Cell Biology
Faculty of Science Engineering And Technology

Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413

16 years

MOLECULAR BIOLOGY, CELL BIOLOGY, GENOMICS & PROTEOMICS
BTE 2501, BTE 6503, BTH 2401: Molecular Biology
BTH 2304, BLS 2303: Genetics and Cell Biology
SCT 2309, SCT4309: Genomics and Proteomics
SPHINGOLIPID BIOLOGY, CANCER, MOLECULAR BIOLOGY and CELL SIGNALING, LIPIDOMICS and TRANSCRIPTOMICS
DECIPHERING THE INTRICACIES OF SPHINGOLIPID SIGNALING DURING CANCER PROGRESSION,
REGULATORY MECHANISMS IN TUMORS IN RESPONSE TO NANOMEDICINE.

Publications:

1. Pal S., Medatwal N., Kumar S., Kar A., Komalla V., Yavvari P.S., Mishra D.K., Malakar D., Pillai M., Srivastava A., Sharma R.D., Sengupta S., Dasgupta U.,* and Bajaj A.* (2019) A localized chimeric hydrogel therapy targets tumor microenvironment through alteration of sphingolipid metabolism. ACS Central Science 5, 1648-1662

2. Kumar S., Thakur J., Yadav K., Mitra M., Pal S., Ray A., Gupta S., Medatwal N., Gupta R., Mishra D., Rani P., Padhi S., Sharma P., Kapil A., Srivastava A., Dasgupta U., Priyakumar U.D., Thukral L., and Bajaj A.* (2019) Cholic Acid-Derived Amphiphile can Combat Gram-Positive Bacteria-mediated Infections via Disintegration of Lipid Clusters. ACS Biomater. Sci. Eng. 5, 9, 4764-4775

3. Dasgupta, U., Bamba, T, Chiantia, S., Karim, P., Tayoun, A.N., Yonamine, I., Rawat, S.S., Rao, R.P., Nagashima, K., Fukusaki, E., Puri, V., Dolph, P.J., Schwille, P., Acharya, J.K., Acharya, U. (2009) Ceramide kinase regulates phospholipase C and phosphatidylinositol 4, 5, bisphosphate in phototransduction. Proc Natl Acad Sci U S A. 106(47):20063-8.

4. Acharya, J.K., Dasgupta, U., Rawat, S.S., Yuan, C., Sanxaridis, P.D., Yonamine, I., Karim, P., Nagashima, K., Brodsky, M., Tsunoda, S., Acharya, U (2008) Cell Non-Autonomous Function of Ceramidase in Photoreceptor homeostasis. Neuron 57(1):69-79
Dasgupta, U., Dixit B.L.,Rusch M., Selleck S., The I. (2007) Functional conservation of the human EXT1 tumor suppressor gene and its Drosophila homologue tout velu. Development Genes and Evolution 8: 555-561.

5. Dasgupta U., Jain M., Tyagi A.K and Khurana J.P. (2005) Regulatory elements for light-dependent and organ-specific expression of Arabidopsis thaliana PSBO1 gene encoding 33 kDa polypeptide of the oxygen-evolving complex. Plant Science 168:1633-1642.

6. Khurana J.P., Dasgupta U., Laxmi A., Kumar, D., and Paul L.K. (2004) Light control of plant development by phytochromes: a perspective. Proceedings of Indian National Science Academy B70:375-399.
MOLECULAR BIOLOGY, CELL BIOLOGY
Member of Society of Biological Chemists, India (SBCI)
Member of Indian society of Translational Research (ISTR)
Member Secretary, Institutional Ethics Committee (AUH)
Member, Institutional Bio-Safety Committee (AUH)
Faculty-in-charge- Amity Lipidomics Research Facility (CIRF committee, AUH)
Women Scientist Award- DBT BioCaRE(2017)
Early Career Research Award (2017)
Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Govt. of India

Grants:

1. Unravelling the Role of mTORC2 in Regulation of Sphingolipid Biosynthesis in Mammalian Breast Cancer Cells; funded by Department of Biotechnology.
DBT, BioCaRE (2017-2020).

2. Comparative Sphingolipid Profiling of Breast Cancer Cell and Tissue Types for Identification of Potential Metastatic Biomarkers; funded by Department of Science and Technology.
SERB, ECR (2017-2020)

3. Combating topical and medical device related multidrug related fungal infections using molecularly engineered anti-fungal hydrogel.
DBT, EMR (2018-2021)
Faculty of Science Engineering And Technology
Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413