Faculty

Dr. Amit Kumar Pandey
Assistant Professor
Molecular Biology, Non-Coding RNA, Cell Biology
Faculty of Science Engineering And Technology

Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413

Post-Doctoral experience.
1. Cancer Science Institute of Singapore, National University Singapore, Singapore (March 2013 to March 2018)
Identifying the regulators of TIP60.
2. Max Delbruck Centre for Molecular Medicine, Berlin, Germany (June 2012- Jan 2013)
Role of AGO2 in pancreatic ß cell secretome and expansion.

a) Btech-Mtech Dual Biotechnology- 7thsem - Molecular Cell Biology
b) Btech-Mtech Dual Biotechnology- 8thsem - Genomics and Proteomics
c) Btech Bioinformatics 5thsem- Genetic Engineering
d) BSc Biological Sciences 6thsem- Genomics and Proteomics
e) BSc Biotechnology 6thsem- Genomics and Proteomics
f) Btech-Mtech Dual Biotechnology- 4thsem - Structural Biology
g) BSc-MSc Dual Biotechnology 6thsem- Genomics and Proteomics
h) BSc Biotechnology 3rd Sem- Genetics and Cell Biology
i) PhD coursework- Research Methodology
j) PhD Coursework- Molecular Biology
Role of Non-coding RNAs in cancer

Publications:

1. Rajagopalan D, Pandey AK, Xiuzhen MC, Lee KK, Hora S, Zhang Y, Chua BH,Kwok HS, Bhatia SS, Deng LW, Tenen DG, Kappei D, Jha S. TIP60 repressestelomerase expression by inhibiting Sp1 binding to the TERT promoter. PLoSPathog. 2017 Oct 18; 13(10):e1006681. (IF-6.67)

2. Zhang Y, Subbaiah VK, Rajagopalan D, Tham CY, Abdullah LN, Toh TB, Gong M,Tan TZ, Jadhav SP, Pandey AK, Karnani N, Chow EKH, Thiery, JP, Jha S.TIP60inhibits metastasis by ablating DNMT1-SNAIL2 driven epithelial- mesenchymaltransition program. Journal of Molecular Cell Biology. 2016 (IF-6.459)

3. Pandey AK, Zhang Y, Zhang S, Li Y, Tucker-Kellogg G, Yang H, Jha S. TIP60-miR-22 axis as a prognostic marker of breast cancer progression. Oncotarget.2015 Dec 1; 6(38):41290-306 (IF-6.359).

4. Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M,Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL,Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN. Argonaute2 mediates compensatory expansion of the pancreatic ß cell. Cell Metab. 2014 Jan 7; 19(1):122-34 (IF-17.565).

5. Tattikota SG*, Sury MD*, Rathjen T*, Wessels HH, Pandey AK, You X, Becker C, Chen W, Selbach M, Poy MN. Argonaute2 regulates the pancreatic ß-cell secretome. Mol Cell Proteomics. 2013 May; 12(5):1214-25. (IF-6.564) (*-Shared authorship).

6. Kaur K, Pandey AK, Srivastava S, Srivastava AK, Datta M. Comprehensive miRNome and in silico analyses identify the Wnt signaling pathway to be altered in the diabetic liver. Mol Biosyst. 2011 Dec; 7(12):3234-44. (IF-3.35).

7. Pandey AK, Verma G, Vig S, Srivastava S, Srivastava AK, Datta M. miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells. Mol Cell Endocrinol. 2011 Jan 30; 332(1-2):125-33 (IF- 4.405).

8. Pandey AK, Munjal N, Datta M. Gene expression profiling and network analysis reveals lipid and steroid metabolism to be the most favoured by TNFalpha in HepG2 cells. PLoS One. 2010 Feb 4; 5(2):e9063 (IF-3.234).

9. Pandey AK, Bhardwaj V, Datta M. Tumour necrosis factor-alpha attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells. FEBS J. 2009 Jul; 276(14):3757-69 (IF-4.001).

10. Pandey AK, Agarwal P, Kaur K, Datta M. MicroRNAs in diabetes: tiny players in big disease. Cell Physiol Biochem. 2009; 23(4-6):221-32 (IF- 3.55).
Molecular Biology
Genetic Engineering
Adhoc Reviewer (Journal)
o 3 Biotech
o Cell cycle
o Life Sciences
o Cancer Letter
o BMC Cancer
o Bioscience Reports
oMolecular Therapy - Nucleic Acids o FrontiersinPharmacology
o OncoTargetsandTherapy
o BiologicalResearch
o BiochemicalSocietyTransactionso PLOSONE
o PharmacologicalResearch
Reviewer of funding agencies and Journals
• Science and Engineering Research Board (SERB),India
• Review Editor for Frontiers in Molecular Biosciences
• Editor PlosOne
1. Mechanistic Involvement of Long Non-Coding RNAs in Oncotherapeutics Resistance in Triple- Negative Breast Cancer. S Kansara, V Pandey, PE Lobie, G Sethi, M Garg, AK Pandey, Cells 9 (6), 1511 (IF-5.65)
2. Kirtonia A, Gala K, Fernandes SG, Pandya G, Pandey AK, Sethi G, Khattar E, Garg M . Repurposing of drugs: An attractive pharmacological strategy for cancer therapeutics. Semin Cancer Biol. 2020 May 4:S1044-579X(20)30094-8 (IF-9.658)
3. Pal S, Garg M, Pandey AK. Deciphering the mounting complexity of the p53 regulatory network in correlation to lncRNAs in ovarian cancer. Cells.2020 Feb 25;9(3):527 (IF 5.65)
4. Pandey AK, Zhang Y, Zhang S, Li Y, Tucker-Kellogg G, Yang H, Jha S. TIP60- miR-22 axis as a prognostic marker of breast cancer progression. Oncotarget. 2015 Dec 1; 6(38):41290- 306 (IF-5.128).
5. TattikotaSG,RathjenT,McAnultySJ,WesselsHH,AkermanI,vandeBuntM,HausserJ, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom- Feuerstein R, Aberdam D, Poy MN. Argonaute2 mediates compensatory expansion of the pancreatic ß cell. Cell Metab. 2014 Jan 7; 19(1):122-34(IF-17.565).
6. Pandey AK, Verma G, Vig S, Srivastava S, Srivastava AK, Datta M. miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells. Mol Cell Endocrinol. 2011 Jan 30; 332(1-2):125- 33 (IF- 4.405).
7. Pandey AK, Munjal N, Datta M. Gene expression profiling and network analysis reveals lipid and steroid metabolism to be the most favoured by TNFalpha in HepG2 cells. PLoS One. 2010 Feb 4; 5(2):e9063 (IF-3.234).
8. PandeyAK, BhardwajV, DattaM.Tumournecrosisfactor-alphaattenuatesinsulinaction on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells. FEBS J. 2009 Jul; 276(14):3757-69 (IF- 4.001).
9. Pandey AK, Agarwal P, Kaur K, Datta M. MicroRNAs in diabetes: tiny players in big disease. Cell PhysiolBiochem. 2009; 23(4-6):221-32 (IF- 3.55).
Faculty of Science Engineering And Technology
Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413