Dr. Atanu Banerjee
Assistant Professor
Biochemistry, Microbiology, Bioinformatics
Faculty of Science Engineering And Technology

Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413

3+ years of Post Ph.D. Research/Teaching experience

Biochemistry BTE2302
Biochemistry lab BTE2306
Biophysics and Structural Biology BTH4302
Biophysics and Structural Biology BTH6902
In silico analysis of Biomolecules BTH2405
In silico analysis of Biomolecules lab BTH2408
Recombinant DNA technology BTE4201
Research methodology and computer applications(part of PhD coursework) BTC5001
Genomics and Proteomics SCT4305
Genomics and Proteomic Algorithms SCT2306
Microbial transport systems, Antifungal resistance mechanisms, Sequence and structural bioinformatics of membrane proteins

1. Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps. Atanu Banerjee*, Alexis Moreno, Mohammad Firoz Khan, Remya Nair, Suman Sharma, Sobhan Sen, Alok Kumar Mondal, Jorgaq Pata, Cédric Orelle, Pierre Falson* and Rajendra Prasad*. BBA-Biomembranes, (2019); https://doi.org/10.1016/j.bbamem.2019.183131 (*corresponding author).

2. Multidrug transporters of Candida species in clinical azole resistance. Rajendra Prasad*, Remya Nair, Atanu Banerjee*. Fungal Genetics and Biology, (2019); Jul 11;132:103252. doi: 10.1016/j.fgb.2019.103252 (*corresponding author).

3. Information theoretic measures and mutagenesis identify a novel linchpin residue involved in substrate selection within the nucleotide-binding domain of an ABCG family exporter Cdr1p. Atanu Banerjee, Poonam Vishwakarma, Antresh Kumar, Andrew M. Lynn* and Rajendra Prasad*. Archives of Biochemistry and Biophysics (2019) 663; 143-150; https://doi.org/10.1016/j.abb.2019.01.013.

4. The E-helix is a central core in a conserved helical bundle involved in Nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily. Poonam Vishwakarma, Atanu Banerjee, Ritu Pasrija, Rajendra Prasad and Andrew M. Lynn. International Journal of Biological Macromolecules (2019) 127; 95-106; https://doi.org/10.1016/j.ijbiomac.2019.01.030.

5. W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans. Atanu Banerjee, Peer Abdul Haseeb Shah, Archana Kumari and Rajendra Prasad. BBA-Biomembranes (2018), Volume 1860, Issue 5, May 2018, Pages 965-972.

6. Molecular basis of substrate polyspecificity of the Candida albicans Mdr1p multidrug/H+ antiporter. Archana Kumari Redhu, Atanu Banerjee, Abdul Haseeb Shah, Alexis Moreno, Manpreet Kaur Rawal, Remya Nair, Pierre Falson and Rajendra Prasad. Journal of Molecular Biology (2018), Volume 430, Issue 5, 2 March, Pages 682-694.

7. A new endogenous overexpression system of multidrug transporters of Candida albicans suitable for structural and functional studies. Atanu Banerjee, Nitesh Kumar Khandelwal, Dominique Sanglard and Rajendra Prasad. Frontiers in Microbiology (2016) DOI: 10.3389/fmicb.2016.00261.

8. pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport. Archana Kumari Redhu, Nitesh Kumar Khandelwal, Atanu Banerjee, Alexis Moreno, Pierre Falson and Rajendra Prasad. Biochemical Journal (2016) 0 1–19 DOI: 10.1042/BCJ20160407.

9. Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric. Manpreet Kaur Rawal, Atanu Banerjee, Abdul Haseeb Shah, Mohammad Firoz Khan, Sobhan Sen, Ajay Kumar Saxena, Brian C. Monk, Richard D. Cannon, Rakesh Bhatnagar, Alok Kumar Mondal and Rajendra Prasad. Scientific Reports (2016) DOI: 10.1038/srep27132

10. ABC transporter Cdr1p harbors charged residues in the intracellular loop and nucleotide-binding domain critical for protein trafficking and drug resistance. Abdul Haseeb Shah, Atanu Banerjee, Manpreet Kaur Rawal, Ajay Kumar Saxena, Alok Kumar Mondal and Rajendra Prasad. FEMS Yeast Research (2015). DOI:https://doi.org/10.1093/femsyr/fov036
Biochemistry, Biophysics and Bioinformatics
Member, Asia-Pacific Bioinformatics Network
Reviewer of Scientific reports (Nature publishing Group), Expert review of anti-infective therapy (Taylor and Francis), Expert opinion on investigational drugs (Taylor and Francis), Journal of Biomolecular Structure and dynamics (Taylor and Francis), and Infection and drug resistance (Dove press).
2019: Visiting Scientist, A.N. Belozersky Institute of Physico-Chemical Biology M.V. Lomonosov Moscow State University, Russia
2019: Start-up Research Grant Award (Life Sciences), Science and Engineering Research Board, Government of India
2017: SERB-DST travel grant to attend Gordon Research Conference: Multidrug efflux systems in Galveston, Texas
2014-2017: Senior Research Fellowship, Council of Scientific and Industrial Research, Government of India
2012-2014: Junior Research Fellowship, Council of Scientific and Industrial Research, Government of India

Project details:

1. Mitigating the impact of antifungal resistance in the emerging pathogen Candida auris by piggybacking its peptide permease as an antifungal delivery system (Funding agency: SERB; ongoing)
2. Insights into the efflux pump arsenal of the emerging pathogen C. auris and its implication in high order of antifungal resistance and virulence (Funding agency: DBT; financial sanction awaited)
Faculty of Science Engineering And Technology
Amity University Haryana, Amity Education Valley, Pachgaon, Manesar, Gurgaon, Haryana 122413