Microbial transport systems, Antifungal resistance mechanisms, Sequence and structural bioinformatics of membrane proteins
Publications:
1. Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps. Atanu Banerjee*, Alexis Moreno, Mohammad Firoz Khan, Remya Nair, Suman Sharma, Sobhan Sen, Alok Kumar Mondal, Jorgaq Pata, Cédric Orelle, Pierre Falson* and Rajendra Prasad*. BBA-Biomembranes, (2019); https://doi.org/10.1016/j.bbamem.2019.183131 (*corresponding author).
2. Multidrug transporters of Candida species in clinical azole resistance. Rajendra Prasad*, Remya Nair, Atanu Banerjee*. Fungal Genetics and Biology, (2019); Jul 11;132:103252. doi: 10.1016/j.fgb.2019.103252 (*corresponding author).
3. Information theoretic measures and mutagenesis identify a novel linchpin residue involved in substrate selection within the nucleotide-binding domain of an ABCG family exporter Cdr1p. Atanu Banerjee, Poonam Vishwakarma, Antresh Kumar, Andrew M. Lynn* and Rajendra Prasad*. Archives of Biochemistry and Biophysics (2019) 663; 143-150; https://doi.org/10.1016/j.abb.2019.01.013.
4. The E-helix is a central core in a conserved helical bundle involved in Nucleotide binding and transmembrane domain intercalation in the ABC transporter superfamily. Poonam Vishwakarma, Atanu Banerjee, Ritu Pasrija, Rajendra Prasad and Andrew M. Lynn. International Journal of Biological Macromolecules (2019) 127; 95-106; https://doi.org/10.1016/j.ijbiomac.2019.01.030.
5. W1038 near D-loop of NBD2 is a focal point for inter-domain communication in multidrug transporter Cdr1 of Candida albicans. Atanu Banerjee, Peer Abdul Haseeb Shah, Archana Kumari and Rajendra Prasad. BBA-Biomembranes (2018), Volume 1860, Issue 5, May 2018, Pages 965-972.
6. Molecular basis of substrate polyspecificity of the Candida albicans Mdr1p multidrug/H+ antiporter. Archana Kumari Redhu, Atanu Banerjee, Abdul Haseeb Shah, Alexis Moreno, Manpreet Kaur Rawal, Remya Nair, Pierre Falson and Rajendra Prasad. Journal of Molecular Biology (2018), Volume 430, Issue 5, 2 March, Pages 682-694.
7. A new endogenous overexpression system of multidrug transporters of Candida albicans suitable for structural and functional studies. Atanu Banerjee, Nitesh Kumar Khandelwal, Dominique Sanglard and Rajendra Prasad. Frontiers in Microbiology (2016) DOI: 10.3389/fmicb.2016.00261.
8. pHluorin enables insights into the transport mechanism of antiporter Mdr1: R215 is critical for drug/H+ antiport. Archana Kumari Redhu, Nitesh Kumar Khandelwal, Atanu Banerjee, Alexis Moreno, Pierre Falson and Rajendra Prasad. Biochemical Journal (2016) 0 1–19 DOI: 10.1042/BCJ20160407.
9. Newly identified motifs in Candida albicans Cdr1 protein nucleotide binding domains are pleiotropic drug resistance subfamily-specific and functionally asymmetric. Manpreet Kaur Rawal, Atanu Banerjee, Abdul Haseeb Shah, Mohammad Firoz Khan, Sobhan Sen, Ajay Kumar Saxena, Brian C. Monk, Richard D. Cannon, Rakesh Bhatnagar, Alok Kumar Mondal and Rajendra Prasad. Scientific Reports (2016) DOI: 10.1038/srep27132
10. ABC transporter Cdr1p harbors charged residues in the intracellular loop and nucleotide-binding domain critical for protein trafficking and drug resistance. Abdul Haseeb Shah, Atanu Banerjee, Manpreet Kaur Rawal, Ajay Kumar Saxena, Alok Kumar Mondal and Rajendra Prasad. FEMS Yeast Research (2015). DOI:https://doi.org/10.1093/femsyr/fov036