Dr. Ravi Datta Sharma

Assistant Professor

Amity Institute of Biotechnology, Gurgaon (Manesar)

Computtional Biology, Bioinformatics and Data Science
Faculty of Science Engineering And Technology

Amity University Gurgaon, Panchgaon, Manesar, Gurgaon 122413

DSC4302: Deep Learning & Neural Networks
DSC4108: Introduction to Linux
SCT4204: Biological Programming-II (Bioinformatics)
BIF2604: Immuno-informatics
BTE2610:Artificial Neural Network
BTH4305: Bioinformatics and Computational Biology
BTE2609: Molecular Modeling
BTE2504: Bioinformatics
The major focus has been in developing algorithm to resolve the problems in Genomics and transcriptomics focused on finding alternative splicing and its role in diseases, aging underlying in different organism and species. The group is also interested in understanding structural biology/system biology of several proteins using Molecular dynamics and omics data.The group also have a keen interest in applying data science technique such as deep learning and artificial intelligence to genomics and proteomics data.


1. Multiple transcription factors co-regulate the Mycobacterium tuberculosis adaptation, response to Vitamin C, Malobi Nandi, Kriti Sikri, Neha Chaudhary, Shekhar Chintamani Mande, Ravi Datta Sharma & Jaya Sivaswami Tyagi, BMC Genomics 20, Article number: 887(2019),

2. A Localized Chimeric Hydrogel Therapy Combats Tumor Progression through Alteration of Sphingolipid Metabolism, Sanjay Pal, Nihal Medatwal, Sandeep Kumar, Animesh Kar,Varsha Komalla,Prabhu Srinivas Yavvari, Deepakkumar Mishra, Zaigham Abbas Rizvi, Shiv Nandan, Dipankar Malakar,Manoj Pillai,Amit Awasthi, Prasenjit Das,Ravi Datta sharma, Aasheesh Srivastava, Sagar Sengupta, Ujjaini Dasgupta, and Avinash Bajaj, ACS Cent. Sci. 2019, 5, 10, 1648-1662, DOI: 10.1021/acscentsci.9b00551, 2019

3. Aberrant splicing of BAF45d in gliomas: a link between splicing regulation and transcription, Guillermo Aldave, Marisol Gonzalez-Huarriz,Angel Rubio, Juan Pablo Romero, Datta Ravi, Bele´n Min~ana, Mar Cuadrado-Tejedor, Ana Garci´a- Osta, Roeland Verhaak, Enric Xipell, Naiara Martinez-Ve´lez, Arlet Acanda de la Rocha, Montserrat Puigdelloses, Marc Garci´a-Moure, Miguel Marigil, Jaime Ga´llego Pe´rez-Larraya, Oskar Mari´n-Bejar, Maite Huarte, Maria Stella Carro, Roberto Ferrarese, Cristobal Belda-Iniesta, Angel Ayuso, Ricardo Prat-Aci´n, Fernando Pastor, Ricardo Di´ez- Valle, Sonia Tejada, and Marta M. Alonso, Neuro-Oncology (2018), Volume 20, Issue 7, July 2018, Pages 930–941 DOI:10.1093/neuonc/noy007

4. Differential alternative splicing coupled to nonsense-mediated decay of mRNA ensures dietary restriction-induced longevity, Syed Tabrez, Ravi Sharma, Vaibhav Jain, Atif Siddiqui, and Arnab Mukhopadhyay, Nature Communications 8, Article number: 306 (2017), DOI:10.1038/s41467-017-00370-5

5. A LARGE-SCALE ANALYSIS OF ALTERNATIVE SPLICING REVEALS A KEY ROLE OF QKI IN LUNG CANCER, Fernando J de Miguel, Ravi D Sharma et al., Molecular Oncology, 2016, Nov;10(9):1437-1449. DOI:10.1016/j.molonc.2016.08.001,

6. Identification of alternative splicing events regulated by the oncogenic factor SRSF1 in lung cancer, Fernando J de Miguel*, Ravi D Sharma*, Mari´a J Pajares, Luis M Montuenga, Angel Rubio, Ruben Pio, Cancer Res (2014)74:1105-1115, DOI: 10.1158/0008-5472.CAN-13-1481) (* Joint first author).
Association of Microbiologist of India (AMI)
Fedora Project (Open Source)
• Editorial Board Member- Exploratory biotechnology research
• Member of Advisory Committee, Society for Green Environment, New Delhi, India
• Reviewer for Journal of Molecular modelling, Journal of Bioscience, BioCell
Doctoral fellowship awarded by University of Navarra, Spain
Post-doctoral fellowship (F+)awarded by KU-Leuven,Belgium


1. “A Computational Software to find biomarkers using alternative splicing as a tool”,DBT-[BT/PR27108/BID/7/820/2017] as PI, Sanction (Rs.1996063/-), 19- 09-2018
2. "Alternate splicing in clinical drug resistance in pathogenic Candida", DST-SERB [EMR /2017/001907] as Co-PI, Sanction amount (Rs. 2470000/-), 22-10-2018
3. National level training Programme: In-house short term training/FDP programmes for faculty/UG/PG/Doctoral students of two weeks duration under ICPS Programme of DST, Co-PI, 30-03-2019, Sanction amount: Rs. (9,00,000/-)
Faculty of Science Engineering And Technology
Amity University Gurgaon, Panchgaon, Manesar, Gurgaon 122413